HHS peptide policy checker

Is your peptide covered by the October 28, 2026 HHS policy? Tap 3 answers. Get a clear result you can share.

Short answer: HHS will not act against licensed US pharmacies and doctors that compound 6 peptides (BPC-157, TB-500, KPV, MOTS-c, Semax, epitalon) for a patient with a prescription, in set forms and under 10 conditions. Blends, other peptides and "research use only" products are not covered. None is FDA approved.

By the Peptide Science Desk Editorial TeamFact-checked against FDA and official sources · Oct 31, 2026Not yet reviewed by a licensed clinician. How we check facts

1What is it?

2How is it taken?

3Where does it come from?

Covered, with conditions

BPC-157 as a shot from a US pharmacy with a prescription

HHS says it will not take action if the pharmacy or doctor meets all 10 conditions below. It is still not FDA approved.

✓On the HHS list of 6 peptides (Appendix A)
✓Allowed form: BPC-157 acetate as a shot under the skin or into a muscle (Appendix B)
✓Made by a state-licensed pharmacy or doctor for you, with a prescription

Which forms are allowed?

From Appendix B of the HHS policy. Tap a row to check it above.

Shot	Pill	Cream	Nose
✓	✓	✓	–
✓	–	–	–
–	✓	✓	–
✓	–	–	–
–	–	–	✓
✓	–	–	–

Shot means under the skin or into a muscle. Epitalon shots are in short courses with breaks. BPC-157 and KPV pills need proof they are absorbed well enough by mouth in people. Semax is the free base form; the others are acetate salts.

Key dates

Oct 28, 2026HHS issued the policy; filed for public inspection
Oct 30, 2026Published in the Federal Register (91 FR 68526, FR Doc. 2026-22192)
About Nov 13, 2026Comments close: 2 weeks after publication (our count; the notice gives no exact date)
After thatInterim: HHS may change it, for example if a safety problem shows up

Docket HHS-OASH-2026-0496 on regulations.gov. HHS calls it a draft, interim policy that does not create rights and is not binding. Live FDA peptide policy tracker · News: HHS peptide policy covers 6 peptides

Not medical or legal advice. This tool explains a federal enforcement policy in plain words. State laws can differ. Ask your doctor before using any peptide, and a lawyer for legal questions.

FAQ

Is BPC-157 legal now?

Only in a narrow way. Since Oct 28, 2026, HHS says it will not act against a state-licensed pharmacy, federal facility or licensed doctor that compounds BPC-157 for a patient with a prescription, if 10 conditions are met. BPC-157 is still not FDA approved, and the policy does not cover "research use only" products.

Do I need a prescription for BPC-157?

Yes, under this policy. It covers only compounding by a licensed pharmacy, federal facility or doctor, and HHS says all other drug-law rules still apply, including a prescription for an individual patient. Buying "research use only" vials is not covered.

Is TB-500 legal now?

TB-500 acetate is on the HHS list as a shot under the skin or into a muscle, compounded by a licensed pharmacy or doctor with a prescription. Other forms and "research use only" sellers are not covered. It is not FDA approved.

Is Semax covered by the HHS policy?

Yes, but only Semax (free base) as a nose spray, compounded for a patient with a prescription. Semax shots are not covered. Semax is not FDA approved.

Are Wolverine, GLOW and KLOW blends covered?

No. The policy allows only 1 peptide from its list per product. Wolverine mixes BPC-157 and TB-500. GLOW and KLOW also contain GHK-Cu, which is not on the list.

Is DSIP covered?

No. DSIP (emideltide) is not one of the 6 peptides on the HHS list. Neither are GHK-Cu, CJC-1295, ipamorelin or Selank.

When can I comment on the HHS peptide policy?

The Federal Register notice was published Oct 30, 2026 (91 FR 68526). It says comments are open for 2 weeks after publication. By our count that is about Nov 13, 2026; the notice does not print an exact date. Comments go to regulations.gov, docket HHS-OASH-2026-0496.

Sources

Checked October 30, 2026. Not medical or legal advice. Disclaimer · How we check facts