PT-141 (Bremelanotide, Vyleesi)

Proven in people & FDA approved

Bremelanotide is FDA-approved as Vyleesi, but only for one use: low sex drive in some women before menopause.

Pending medical review Updated October 16, 2026

What is it?

PT-141 is another name for bremelanotide. It is a peptide medicine. The approved brand is Vyleesi. You need a doctor’s prescription.

Why do people use it?

Vyleesi is approved for women who have not gone through menopause and who have low sex drive that upsets them, when it is not caused by another health problem, relationship problems, or another medicine.

Does it really work?

It is FDA-approved for that one use. The label says it is not approved for women after menopause, and it is not approved for men.

Is it safe? Side effects

  • The most common side effects on the label are feeling sick (nausea), red or hot face (flushing), skin reactions where the shot goes in, headache, and throwing up.
  • It can raise blood pressure for a short time and slow the heart rate.
  • Some people got dark spots on the skin, like the face, gums, or breasts.

Talk to your doctor

Do not start any peptide on your own. Ask a doctor first. We never share doses or tell you where to buy. Print our doctor questions sheet.

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FAQ

What is PT-141 (Bremelanotide, Vyleesi)?

PT-141 is another name for bremelanotide. It is a peptide medicine. The approved brand is Vyleesi. You need a doctor’s prescription.

Does PT-141 (Bremelanotide, Vyleesi) work?

It is FDA-approved for that one use. The label says it is not approved for women after menopause, and it is not approved for men.

Is PT-141 (Bremelanotide, Vyleesi) legal in the US?

Yes, Vyleesi is FDA-approved for its labeled use. (The FDA is the US agency that checks if medicines are safe and work.) Products sold online as "PT-141 for research" are not the approved medicine.

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Sources

Not medical advice. Medical disclaimer.